Idiopathic pulmonary fibrosis: CT and risk of death.

ABSTRACT:

Purpose

To investigate the prognostic value of quantitative computed tomographic (CT) scoring for the extent of fibrosis or emphysema in the context of a clinical model that includes the gender, age, and physiology ( GAP gender, age, and physiology model) of the patient.

Materials and methods

Study cohorts were approved by local institutional review boards, and all patients provided written consent. This was a retrospective cohort study that included 348 patients (246 men, 102 women; mean age, 69 years ± 9) with idiopathic pulmonary fibrosis from two institutions. Fibrosis and emphysema visual scores were independently determined by two radiologists. Models were based on competing risks regression for death and were evaluated by using the C index and reclassification improve

SUBMITTER: Ley B 

PROVIDER: S-EPMC4334234 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature