Phenotypic and genotypic analysis of benzimidazole resistance in the ovine parasite Nematodirus battus.

ABSTRACT: Benzimidazole resistance is common amongst many ovine trichostrongylid nematodes species globally. Although anthelmintics have been used for over half a century in some areas of the world for the control of Nematodirus battus, resistance has never been detected. Veterinary investigations conducted in 2010 demonstrated reduced efficacy in a flock that had been treated previously with fenbendazole (FBZ), suggesting probable resistance in N. battus. Infective larvae (L3; designated MNba2) were generated from the original material to conduct a controlled efficacy test (CET). Faecal egg counts showed an average of 37% reduction in the FBZ treated group 7 days post treatment compared to the untreated lambs. Average worm burden results showed no reduction after FBZ treatment compared to the untre

SUBMITTER: Morrison AA 

PROVIDER: S-EPMC4334412 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature