Digoxin and risk of death in adults with atrial fibrillation: the ATRIA-CVRN study.

ABSTRACT:

Background

Digoxin remains commonly used for rate control in atrial fibrillation, but limited data exist supporting this practice and some studies have shown an association with adverse outcomes. We examined the independent association between digoxin and risks of death and hospitalization in adults with incident atrial fibrillation and no heart failure.

Methods and results

We performed a retrospective cohort study of 14,787 age, sex, and high-dimensional propensity score-matched adults with incident atrial fibrillation and no previous heart failure or digoxin use in the AnTicoagulation and Risk factors In Atrial fibrillation-Cardiovascular Research Network (ATRIA-CVRN) study within Kaiser Permanente Northern and Southern California. We examined the independent association b

SUBMITTER: Freeman JV 

PROVIDER: S-EPMC4334705 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature