Analysis of the effect of locally applied inhomogeneous static magnetic field-exposure on mouse ear edema--a double blind study.

ABSTRACT: The effect static magnetic field (SMF)-exposure may exert on edema development has been investigated. A 6 h long whole-body (WBSMF) or local (LSMF), continuous, inhomogeneous SMF-exposure was applied on anesthetized mice in an in vivo model of mustard oil (MO)-induced ear edema. LSMF was applied below the treated ear, below the lumbar spine, or below the mandible. Ear thickness (v) was checked 8 times during the exposure period (at 0, 0.25, 1, 2, 3, 4, 5, and 6 h). The effect size of the applied treatment (η) on ear thickness was calculated by the formula η = 100% × (1-v(j)/v(i)), where group i is the control group and j is the treated group. Results showed that MO treatment in itself induced a significant ear edema with an effect of 9% (p<0.001). WBSMF or LSMF on the spine in combination

SUBMITTER: Kiss B 

PROVIDER: S-EPMC4335006 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature