Cost-effectiveness of CT screening in the National Lung Screening Trial.

ABSTRACT:

Background

The National Lung Screening Trial (NLST) showed that screening with low-dose computed tomography (CT) as compared with chest radiography reduced lung-cancer mortality. We examined the cost-effectiveness of screening with low-dose CT in the NLST.

Methods

We estimated mean life-years, quality-adjusted life-years (QALYs), costs per person, and incremental cost-effectiveness ratios (ICERs) for three alternative strategies: screening with low-dose CT, screening with radiography, and no screening. Estimations of life-years were based on the number of observed deaths that occurred during the trial and the projected survival of persons who were alive at the end of the trial. Quality adjustments were derived from a subgroup of participants who were selected to complete qua

SUBMITTER: Black WC 

PROVIDER: S-EPMC4335305 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature