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Whole-Genome Sequence of a Bordetella pertussis Brazilian Vaccine Strain.

ABSTRACT: Despite the reduction in incidence after vaccination, pertussis disease is still considered a public health problem worldwide, mainly due to recent and potential new outbreaks. We report here the complete genome of the Bordetella pertussis Butantan strain used in the Brazilian National Immunization Program as a whole-cell pertussis antigen to compose vaccines such as DTwP (diphtheria, tetanus, and whole-cell pertussis).

SUBMITTER: Akamatsu MA 

PROVIDER: S-EPMC4335333 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature

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Whole-Genome Sequence of a Bordetella pertussis Brazilian Vaccine Strain.

Akamatsu M A MA   Nishiyama M Y MY   Morone M M   Oliveira U C UC   Bezerra M F B MF   Sakauchi M A MA   Raw I I   Junqueira de Azevedo I L M IL   Kitajima J P JP   Carvalho E E   Ho P L PL  

Genome announcements 20150219 1

Despite the reduction in incidence after vaccination, pertussis disease is still considered a public health problem worldwide, mainly due to recent and potential new outbreaks. We report here the complete genome of the Bordetella pertussis Butantan strain used in the Brazilian National Immunization Program as a whole-cell pertussis antigen to compose vaccines such as DTwP (diphtheria, tetanus, and whole-cell pertussis). ...[more]

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