Interstitial diffuse radiance spectroscopy of gold nanocages and nanorods in bulk muscle tissues.

ABSTRACT: Radiance spectroscopy was applied to the interstitial detection of localized inclusions containing Au nanocages or nanorods with various concentrations embedded in porcine muscle phantoms. The radiance was quantified using a perturbation approach, which enabled the separation of contributions from the porcine phantom and the localized inclusion, with the inclusion serving as a perturbation probe of photon distributions in the turbid medium. Positioning the inclusion at various places in the phantom allowed for tracking of photons that originated from a light source, passed through the inclusion's location, and reached a detector. The inclusions with high extinction coefficients were able to absorb nearly all photons in the range of 650-900 nm, leading to a spectrally flat radiance signal.

SUBMITTER: Grabtchak S 

PROVIDER: S-EPMC4335609 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature