Cognitive function in women with HIV: findings from the Women's Interagency HIV Study.

ABSTRACT:

Objective

In the largest cohort study of neuropsychological outcomes among HIV-infected women to date, we examined the association between HIV status and cognition in relation to other determinants of cognitive function (aim 1) and the pattern and magnitude of impairment across cognitive outcomes (aim 2).

Methods

From 2009 to 2011, 1,521 (1,019 HIV-infected) participants from the Women's Interagency HIV Study (WIHS) completed a comprehensive neuropsychological test battery. We used multivariable regression on raw test scores for the first aim and normative regression-based analyses (t scores) for the second aim. The design was cross-sectional.

Results

The effect sizes for HIV status on cognition were very small, accounting for only 0.05 to 0.09 SD units. The effect of

SUBMITTER: Maki PM 

PROVIDER: S-EPMC4335997 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature