Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine.

ABSTRACT:

Objective

To test the hypothesis that ineffective acute treatment of episodic migraine (EM) is associated with an increased risk for the subsequent onset of chronic migraine (CM).

Methods

In the American Migraine Prevalence and Prevention Study, respondents with EM in 2006 who completed the Migraine Treatment Optimization Questionnaire (mTOQ-4) and provided outcome data in 2007 were eligible for analyses. The mTOQ-4 is a validated questionnaire that assesses treatment efficacy based on 4 aspects of response to acute treatment. Total mTOQ-4 scores were used to define categories of acute treatment response: very poor, poor, moderate, and maximum treatment efficacy. Logistic regression models were used to examine the dichotomous outcome of transition from EM in 2006 to CM in 20

SUBMITTER: Lipton RB 

PROVIDER: S-EPMC4336107 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature