Molecular characterization of influenza viruses collected from young children in Uberlandia, Brazil - from 2001 to 2010.

ABSTRACT:

Background

Influenza remains a major health problem due to the seasonal epidemics that occur every year caused by the emergence of new influenza virus strains. Hemagglutinin (HA) and neuraminidase (NA) glycoproteins are under selective pressure and subjected to frequent changes by antigenic drift. Therefore, our main objective was to investigate the influenza cases in Uberlândia city, Midwestern Brazil, in order to monitor the appearance of new viral strains, despite the availability of a prophylactic vaccine.

Methods

Nasopharyngeal samples were collected from 605 children less than five years of age presenting with acute respiratory disease and tested by immunofluorescence assay (IFA) for detection of adenovirus, respiratory syncytial virus, parainfluenza virus types 1, 2,

SUBMITTER: de Mattos Silva Oliveira TF 

PROVIDER: S-EPMC4336712 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature