Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells.

ABSTRACT:

Background

Silver nanoparticles (AgNPs) possess unique physical, chemical, and biological properties. AgNPs have been increasingly used as anticancer, antiangiogenic, and antibacterial agents for the treatment of bacterial infections in open wounds as well as in ointments, bandages, and wound dressings. The present study aimed to investigate the effects of two different sizes of AgNPs (10 nm and 20 nm) in male somatic Leydig (TM3) and Sertoli (TM4) cells and spermatogonial stem cells (SSCs).

Methods

Here, we demonstrate a green and simple method for the synthesis of AgNPs using Bacillus cereus culture supernatants. The synthesized AgNPs were characterized using ultraviolet and visible absorption spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and tr

SUBMITTER: Zhang XF 

PROVIDER: S-EPMC4337509 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature