Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration.

ABSTRACT: Treatment of the neovascular form of age-related macular degeneration (AMD) has been revolutionized by the introduction of such agents as ranibizumab, bevacizumab, and aflibercept. As a result, the incidence of legal blindness occurring secondary to AMD has fallen dramatically in recent years in many countries. While these agents have undoubtedly been successful in reducing visual impairment and blindness, patients with neovascular AMD typically lose some vision over time, and often lose the ability to read, drive, or perform other important activities of daily living. Efforts are therefore under way to develop strategies that allow for earlier detection and treatment of this disease. In this review, we begin by providing an overview of the rationale for, and the benefits of, early detecti

SUBMITTER: Keane PA 

PROVIDER: S-EPMC4337735 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature