Comparison of mammographic density assessed as volumes and areas among women undergoing diagnostic image-guided breast biopsy.

ABSTRACT:

Background

Mammographic density (MD), the area of non-fatty-appearing tissue divided by total breast area, is a strong breast cancer risk factor. Most MD analyses have used visual categorizations or computer-assisted quantification, which ignore breast thickness. We explored MD volume and area, using a volumetric approach previously validated as predictive of breast cancer risk, in relation to risk factors among women undergoing breast biopsy.

Methods

Among 413 primarily white women, ages 40 to 65 years, undergoing diagnostic breast biopsies between 2007 and 2010 at an academic facility in Vermont, MD volume (cm(3)) was quantified in craniocaudal views of the breast contralateral to the biopsy target using a density phantom, whereas MD area (cm(2)) was measured on the same d

SUBMITTER: Gierach GL 

PROVIDER: S-EPMC4337788 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature