1-1-12 one-step wash-in scheme for desflurane low flow anesthesia: performance without nitrous oxide.

ABSTRACT:

Background

We reported a 1-1-12 wash-in scheme for desflurane-nitrous oxide (N2O) low flow anesthesia that is simple, rapid, and predictable. There remain some situations where N2O should be avoided, which limits the generalizability of this wash-in scheme. The objective of our study was to determine the performance of this scheme in contexts where N2O is not used.

Methods

We recruited 106 patients scheduled for elective surgery under general anesthesia. After induction and intubation, wash-in was started with a fresh gas flow of air:O2 1:1 L/min and a vaporizer concentration of desflurane of 12%. Controlled ventilation was then adjusted to maintain PACO2 at 30-35 mmHg.

Results

The alveolar concentration of desflurane (FAD) rose rapidly from 0% to 6% in 4 minutes in t

SUBMITTER: Sathitkarnmanee T 

PROVIDER: S-EPMC4338778 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature