Estimating time to ESRD using kidney failure risk equations: results from the African American Study of Kidney Disease and Hypertension (AASK).

ABSTRACT:

Background

Planning for renal replacement therapy, such as referral for arteriovenous fistula placement and transplantation, often is guided by level of estimated glomerular filtration rate (eGFR). The use of risk equations might enable more accurate estimation of time to end-stage renal disease (ESRD), thus improving patient care.

Study design

Prospective observational study.

Setting & participants

1,094 participants in the African American Study of Kidney Disease and Hypertension (AASK) cohort.

Predictor

Age, sex, urine protein-creatinine ratio ≥ 1g/g, APOL1 high-risk status, and 3-year antecedent eGFR decline.

Outcome

Cumulative incidence of ESRD from 5 different starting points: eGFR of 30 and 15mL/min/1.73m(2) and 1-year ESRD risk of 5%, 10%, and 20

SUBMITTER: Grams ME 

PROVIDER: S-EPMC4339439 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature