Subcutaneous nerve activity and spontaneous ventricular arrhythmias in ambulatory dogs.

ABSTRACT:

Background

Stellate ganglion nerve activity (SGNA) is important in ventricular arrhythmogenesis. However, because thoracotomy is needed to access the stellate ganglion, it is difficult to use SGNA for risk stratification.

Objective

The purpose of this study was to test the hypothesis that subcutaneous nerve activity (SCNA) in canines can be used to estimate SGNA and predict ventricular arrhythmia.

Methods

We implanted radiotransmitters to continuously monitor left stellate ganglion and subcutaneous electrical activities in 7 ambulatory dogs with myocardial infarction, complete heart block, and nerve growth factor infusion to the left stellate ganglion.

Results

Spontaneous ventricular tachycardia (VT) or ventricular fibrillation (VF) was documented in each dog.

SUBMITTER: Doytchinova A 

PROVIDER: S-EPMC4339615 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature