Moderate weight loss in obese and overweight men preserves bone quality.

ABSTRACT:

Background

Weight loss (WL) negatively affects bone mineral density (BMD) in older populations and has specifically been shown in women.

Objective

In this prospective controlled trial, we examined variables of bone quality and endocrine changes after intentional WL in men.

Design

Thirty-eight overweight and obese [mean ± SD body mass index (in kg/m²): 31.9 ± 4.4; age: 58 ± 6 y] men were recruited to either WL through caloric restriction or weight maintenance (WM) for 6 mo.

Results

There was a -7.9 ± 4.4% and +0.2 ± 1.6% change in body weight in the WL and WM groups, respectively. There was a greater increase in femoral neck and total body BMD and bone mineral content (BMC) in the WM group than in the WL group (P-interaction effect < 0.05). In contrast, there wa

SUBMITTER: Pop LC 

PROVIDER: S-EPMC4340066 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature