Parkinson's disease severity and use of dopaminergic medications.

ABSTRACT:

Background

The effects of dopaminergic therapy in parkinson's disease (PD) can vary depending on the class of medication selected.

Objective

The aim of this post hoc study was to determine if the class of dopaminergic therapy correlated with disease severity in persons with early, treated PD.

Methods

A non-parametric global statistical test (GST) was used to assess the status of participants treated with dopamine agonist (DA) monotherapy, levodopa (LD) monotherapy or combined LD and DA therapy on multiple PD outcomes encompassing motor, cognitive, psychiatric and autonomic function, as well as disability and quality of life.

Results

The outcomes measured at the beginning of the study showed lower disease burden for participants on initial DA monotherapy compare

SUBMITTER: Fang JY 

PROVIDER: S-EPMC4340731 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature