Persistent insomnia is associated with mortality risk.

ABSTRACT:

Background

Insomnia has been associated with mortality risk, but whether this association is different in subjects with persistent vs intermittent insomnia is unclear. Additionally, the role of systemic inflammation in such an association is unknown.

Methods

We used data from a community-based cohort to determine whether persistent or intermittent insomnia, defined based on persistence of symptoms over a 6-year period, was associated with death during the following 20 years of follow-up. We also determined whether changes in serum C-reactive protein (CRP) levels measured over 2 decades between study initiation and insomnia determination were different for the persistent, intermittent, and never insomnia groups. The results were adjusted for confounders such as age, sex, body

SUBMITTER: Parthasarathy S 

PROVIDER: S-EPMC4340773 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature