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A bacterial mutant library as a tool to study the attack of a defensin peptide.


ABSTRACT: Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

SUBMITTER: Moser S 

PROVIDER: S-EPMC4341900 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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A bacterial mutant library as a tool to study the attack of a defensin peptide.

Moser Simone S   Chileveru Haritha R HR   Tomaras Jill J   Nolan Elizabeth M EM  

Chembiochem : a European journal of chemical biology 20141127 18


Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host. ...[more]

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