Value-based reimbursement decisions for orphan drugs: a scoping review and decision framework.

ABSTRACT:

Background

The rate of development of new orphan drugs continues to grow. As a result, reimbursing orphan drugs on an exceptional basis is increasingly difficult to sustain from a health system perspective. An understanding of the value that societies attach to providing orphan drugs at the expense of other health technologies is now recognised as an important input to policy debates.

Objectives

The aim of this work was to scope the social value arguments that have been advanced relating to the reimbursement of orphan drugs, and to locate these within a coherent decision-making framework to aid reimbursement decisions in the presence of limited healthcare resources.

Methods

A scoping review of the peer reviewed and grey literature was undertaken, consisting of seven p

SUBMITTER: Paulden M 

PROVIDER: S-EPMC4342524 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature