Noninvasive test for tuberculosis detection among primates.

ABSTRACT: Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

SUBMITTER: Wolf TM 

PROVIDER: S-EPMC4344255 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature