Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.

ABSTRACT: We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012-2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.

SUBMITTER: Isozumi R 

PROVIDER: S-EPMC4344268 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature