Palatogenesis and cutaneous repair: A two-headed coin.

ABSTRACT:

Background

The reparative mechanism that operates following post-natal cutaneous injury is a fundamental survival function that requires a well-orchestrated series of molecular and cellular events. At the end, the body will have closed the hole using processes like cellular proliferation, migration, differentiation and fusion.

Results

These processes are similar to those occurring during embryogenesis and tissue morphogenesis. Palatogenesis, the formation of the palate from two independent palatal shelves growing towards each other and fusing, intuitively, shares many similarities with the closure of a cutaneous wound from the two migrating epithelial fronts.

Conclusions

In this review, we summarize the current information on cutaneous development, wound healing, pala

SUBMITTER: Biggs LC 

PROVIDER: S-EPMC4344910 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature