Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines.

ABSTRACT:

Background

Posttraumatic Stress Disorder (PTSD) is a major public health concern, especially given the recent wars in Iraq and Afghanistan. Nevertheless, despite a sharp increase in the incidence of psychiatric disorders in returning veterans, empirically based prevention strategies are still lacking. To develop effective prevention and treatment strategies, it is necessary to understand the underlying biological mechanisms contributing to PTSD and other trauma related symptoms.

Methods

The "Marine Resiliency Study II" (MRS-II; October 2011-October 2013) Neurocognition project is an investigation of neurocognitive performance in Marines about to be deployed to Afghanistan. As part of this investigation, 1195 Marines and Navy corpsmen underwent a fear conditioning and extinct

SUBMITTER: Acheson DT 

PROVIDER: S-EPMC4345165 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature