Regioselective C-H bond amination by aminoiodanes.

ABSTRACT: A new approach for the direct amination of 2-phenylpyridine derivatives using a diphthalimide-iodane and copper triflate has been developed. A series of different 2-phenylpyridine derivatives were aminated with yields up to 88%. Mechanistic investigations indicate that the reaction proceeds via a copper-mediated single electron transfer.

SUBMITTER: Kantak AA 

PROVIDER: S-EPMC4346094 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature