Assessing sensor accuracy for non-adjunct use of continuous glucose monitoring.

ABSTRACT:

Background

The level of continuous glucose monitoring (CGM) accuracy needed for insulin dosing using sensor values (i.e., the level of accuracy permitting non-adjunct CGM use) is a topic of ongoing debate. Assessment of this level in clinical experiments is virtually impossible because the magnitude of CGM errors cannot be manipulated and related prospectively to clinical outcomes.

Materials and methods

A combination of archival data (parallel CGM, insulin pump, self-monitoring of blood glucose [SMBG] records, and meals for 56 pump users with type 1 diabetes) and in silico experiments was used to "replay" real-life treatment scenarios and relate sensor error to glycemic outcomes. Nominal blood glucose (BG) traces were extracted using a mathematical model, yielding 2,082 BG s

SUBMITTER: Kovatchev BP 

PROVIDER: S-EPMC4346608 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature