Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study.

ABSTRACT:

Background

Low lung function is known to predict mortality in the general population, but the prognostic significance of emphysema on computed tomography (CT) in persons without chronic obstructive pulmonary disease (COPD) is uncertain.

Objective

To determine whether greater emphysema-like lung on CT is associated with all-cause mortality among persons in the general population without airflow obstruction or COPD.

Design

Prospective cohort study.

Setting

Population-based, multiethnic sample from 6 U.S. communities.

Participants

2965 participants aged 45 to 84 years without airflow obstruction on spirometry.

Measurements

Emphysema-like lung was defined as the number of lung voxels with attenuation less than -950 Hounsfield units on cardiac CT and w

SUBMITTER: Oelsner EC 

PROVIDER: S-EPMC4347817 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature