Epidemiologic, clinical, and virologic characteristics of human rhinovirus infection among otherwise healthy children and adults: rhinovirus among adults and children.

ABSTRACT:

Background

human rhinovirus (HRV) is a major cause of influenza-like illness (ILI) in adults and children. Differences in disease severity by HRV species have been described among hospitalized patients with underlying illness. Less is known about the clinical and virologic characteristics of HRV infection among otherwise healthy populations, particularly adults.

Objectives

to characterize molecular epidemiology of HRV and association between HRV species and clinical presentation and viral shedding.

Study design

observational, prospective, facility-based study of ILI was conducted from February 2010 to April 2012. Collection of nasopharyngeal specimens, patient symptoms, and clinical information occurred on days 0, 3, 7, and 28. Patients recorded symptom severity daily

SUBMITTER: Chen WJ 

PROVIDER: S-EPMC4347877 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature