Toward an online cognitive and emotional battery to predict treatment remission in depression.

ABSTRACT:

Purpose

To evaluate the performance of a cognitive and emotional test battery in a representative sample of depressed outpatients to inform likelihood of remission over 8 weeks of treatment with each of three common antidepressant medications.

Patients and methods

Outpatients 18-65 years old with nonpsychotic major depressive disorder (17 sites) were randomized to escitalopram, sertraline or venlafaxine-XR (extended release). Participants scored ≥12 on the baseline 16-item Quick Inventory of Depressive Symptomatology - Self-Report and completed 8 weeks of treatment. The baseline test battery measured cognitive and emotional status. Exploratory multivariate logistic regression models predicting remission (16-item Quick Inventory of Depressive Symptomatology - Self-Report scor

SUBMITTER: Gordon E 

PROVIDER: S-EPMC4348126 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature