Long-term risk of upper gastrointestinal hemorrhage after advanced AKI.

ABSTRACT:

Background and objectives

There are few reports on temporary dialysis-requiring AKI as a risk factor for future upper gastrointestinal bleeding (UGIB). This study sought to explore the long-term association between dialysis-requiring AKI and UGIB.

Design, setting, participants, & measurements

This nationwide cohort study used data from the Taiwan National Health Insurance Research Database. Patients who recovered from dialysis-requiring AKI and matched controls were selected from hospitalized patients age ≥18 years between 1998 and 2006. The cumulative incidences of long-term de novo UGIB were calculated, and the risk factors of UGIB and mortality were identified using time-varying Cox proportional hazard models adjusted for subsequent CKD and ESRD after AKI.

Results

SUBMITTER: Wu PC 

PROVIDER: S-EPMC4348674 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature