A systematic review of glomerular hyperfiltration assessment and definition in the medical literature.

ABSTRACT:

Background and objectives

Evaluation of glomerular hyperfiltration (GH) is difficult; the variable reported definitions impede comparisons between studies. A clear and universal definition of GH would help in comparing results of trials aimed at reducing GH. This study assessed how GH is measured and defined in the literature.

Design, setting, participants, & measurements

Three databases (Embase, MEDLINE, CINAHL) were systematically searched using the terms "hyperfiltration" or "glomerular hyperfiltration". All studies reporting a GH threshold or studying the effect of a high GFR in a continuous manner against another outcome of interest were included.

Results

The literature search was performed from November 2012 to February 2013 and updated in August 2014. From 2013

SUBMITTER: Cachat F 

PROVIDER: S-EPMC4348676 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature