Rhinovirus is an important pathogen in upper and lower respiratory tract infections in Mexican children.

ABSTRACT:

Background

Most of the studies characterizing the incidence of rhinovirus (RV) have been carried out in hospitalized children and in developed countries. In those studies, RV-C has been associated with more severe respiratory tract infections than RV species A and B. In this study we determined the frequency and diversity of RV strains associated with upper and lower respiratory tract infections (URTI, LRTI) in Mexico, and describe the clinical characteristics of the illness associated with different RV species.

Methods

A prospective surveillance of 526 and 250 children with URTI and LRTI was carried out. Respiratory samples were analyzed by RT-PCR for viruses. The 5' untranslated region of the RV genome was amplified and sequenced.

Results

In the case of URTI, 17.5%

SUBMITTER: Aponte FE 

PROVIDER: S-EPMC4349319 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature