Causes and timing of death in extremely premature infants from 2000 through 2011.

ABSTRACT:

Background

Understanding the causes and timing of death in extremely premature infants may guide research efforts and inform the counseling of families.

Methods

We analyzed prospectively collected data on 6075 deaths among 22,248 live births, with gestational ages of 22 0/7 to 28 6/7 weeks, among infants born in study hospitals within the National Institute of Child Health and Human Development Neonatal Research Network. We compared overall and cause-specific in-hospital mortality across three periods from 2000 through 2011, with adjustment for baseline differences.

Results

The number of deaths per 1000 live births was 275 (95% confidence interval [CI], 264 to 285) from 2000 through 2003 and 285 (95% CI, 275 to 295) from 2004 through 2007; the number decreased to 258

SUBMITTER: Patel RM 

PROVIDER: S-EPMC4349362 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature