Gastrointestinal infections and diarrheal disease in Ghanaian infants and children: an outpatient case-control study.

ABSTRACT:

Introduction

Diarrheal diseases are among the most frequent causes of morbidity and mortality in children worldwide, especially in resource-poor areas. This case-control study assessed the associations between gastrointestinal infections and diarrhea in children from rural Ghana.

Methods

Stool samples were collected from 548 children with diarrhea and from 686 without gastrointestinal symptoms visiting a hospital from 2007-2008. Samples were analyzed by microscopy and molecular methods.

Results

The organisms most frequently detected in symptomatic cases were Giardia lamblia, Shigella spp./ enteroinvasive Escherichia coli (EIEC), and Campylobacter jejuni. Infections with rotavirus (adjusted odds ratio [aOR] = 8.4; 95% confidence interval [CI]: 4.3-16.6), C. parvum/homi

SUBMITTER: Krumkamp R 

PROVIDER: S-EPMC4349824 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature