Enhancement of COPD biological networks using a web-based collaboration interface.

ABSTRACT: The construction and application of biological network models is an approach that offers a holistic way to understand biological processes involved in disease. Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory disease of the airways for which therapeutic options currently are limited after diagnosis, even in its earliest stage. COPD network models are important tools to better understand the biological components and processes underlying initial disease development. With the increasing amounts of literature that are now available, crowdsourcing approaches offer new forms of collaboration for researchers to review biological findings, which can be applied to the construction and verification of complex biological networks. We report the construction of 50 biological

SUBMITTER: sbv IMPROVER project team (in alphabetical order) 

PROVIDER: S-EPMC4350443 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature