Increased cardiac index attenuates septic acute kidney injury: a prospective observational study.

ABSTRACT:

Background

The relationship between cardiac output and septic acute kidney injury (AKI) remains unclear. The purpose of this study was to assess the association between the cardiac index (CI) and the renal outcomes in patients with septic shock.

Methods

A one-year prospective cohort study was performed in the surgical and medical ICU of a teaching hospital in Nanjing, China. Twenty-nine septic shock patients who required early goal-directed fluid resuscitation were consecutively included. Pulse indicator continuous cardiac output (PiCCO) device was used to measure hemodynamic parameters before and after early goal-directed therapy (EGDT). Based on CI changes after EGDT, patients were assign to the CI increased group or the CI constant group, respectively. The incidence of po

SUBMITTER: Luo JC 

PROVIDER: S-EPMC4350650 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature