Probabilistic MRI tractography of the optic radiation using constrained spherical deconvolution: a feasibility study.

ABSTRACT:

Background and purpose

Imaging the optic radiation (OR) is of considerable interest in studying diseases affecting the visual pathway and for pre-surgical planning of temporal lobe resections. The purpose of this study was to investigate the clinical feasibility of using probabilistic diffusion tractography based on constrained spherical deconvolution (CSD) to image the optic radiation. It was hypothesized that CSD would provide improved tracking of the OR compared with the widely used ball-and-stick model.

Methods

Diffusion weighted MRI (30 directions) was performed on twenty patients with no known visual deficits. Tractography was performed using probabilistic algorithms based on fiber orientation distribution models of local white matter trajectories. The performance of t

SUBMITTER: Lim JC 

PROVIDER: S-EPMC4351098 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature