Longer RBC storage duration is associated with increased postoperative infections in pediatric cardiac surgery.

ABSTRACT:

Objectives

Infants and children undergoing open heart surgery routinely require multiple RBC transfusions. Children receiving greater numbers of RBC transfusions have increased postoperative complications and mortality. Longer RBC storage age is also associated with increased morbidity and mortality in critically ill children. Whether the association of increased transfusions and worse outcomes can be ameliorated by use of fresh RBCs in pediatric cardiac surgery for congenital heart disease is unknown.

Interventions

One hundred and twenty-eight consecutively transfused children undergoing repair or palliation of congenital heart disease with cardiopulmonary bypass who were participating in a randomized trial of washed versus standard RBC transfusions were evaluated for an as

SUBMITTER: Cholette JM 

PROVIDER: S-EPMC4351137 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature