Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention.

ABSTRACT:

Background

Compared with adults without type 2 diabetes mellitus, those with the disease experience more limitations in their physical functioning (PF). Look AHEAD is a large multicenter trial that examined the effects of an intensive lifestyle intervention (ILI) for weight loss on cardiovascular outcomes compared with diabetes support and education (DSE). Although the current study compared treatment differences between ILI and DSE on PF, the primary goal was to examine whether this effect was moderated by age and history of cardiovascular disease at enrollment.

Methods

Overweight or obese adults with type 2 diabetes mellitus (n = 5,145) were randomly assigned to either ILI or DSE. The mean (±SD) age and % females in ILI was 58.9 years (±6.9) and 59.8%; it was 58.6 years (6

SUBMITTER: Rejeski WJ 

PROVIDER: S-EPMC4351390 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature