Long-term risk of aneurysmal subarachnoid hemorrhage after a negative aneurysm screen.

ABSTRACT:

Objective

The objective was to assess the risk of aneurysmal subarachnoid hemorrhage (aSAH) in the initial 15 years after negative aneurysm screening in persons with one first-degree relative with aSAH.

Methods

From a cohort of first-degree relatives of patients with aSAH who underwent screening between 1995 and 1997 (n = 626), we included those with a negative screening (n = 601). We retrieved all causes of death and sent a questionnaire to screenees who were still alive. If aSAH was reported, we reviewed all medical data. We assessed the incidence of aSAH in this cohort with survival analysis and calculated an incidence ratio by dividing the observed incidence with the age- and sex-adjusted incidence in the general population.

Results

Of the 601 screenees, 3 had aSA

SUBMITTER: Rasing I 

PROVIDER: S-EPMC4351666 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature