The anterior insula shows heightened interictal intrinsic connectivity in migraine without aura.

ABSTRACT:

Objective

We sought to explore whether patients with migraine show heightened interictal intrinsic connectivity within primary sensory networks, the salience network, and a network anchored by the dorsal pons, a region known to be active during migraine attacks.

Methods

Using task-free fMRI and a region-of-interest analysis, we compared intrinsic connectivity patterns in 15 migraineurs without aura to 15 age- and sex-matched healthy controls, focusing on networks anchored by the calcarine cortex, Heschl gyrus, right anterior insula, and dorsal pons, a region active during migraine attacks. We also examined the relationship between network connectivity, migraine frequency, and sensory sensitivity symptoms.

Results

Migraineurs showed increased connectivity between prima

SUBMITTER: Tso AR 

PROVIDER: S-EPMC4352101 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature