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A systematic review of controlled trials of lower-protein or energy-containing infant formulas for use by healthy full-term infants.


ABSTRACT: Infant formulas have historically been developed based on providing macronutrients at intake concentrations approximately matching the composition of human milk. In most countries, targets of 1.4-1.5 g of protein/dL and 20 kcal/oz (67-68 kcal/dL) have been set as the protein and energy concentrations for formulas during the first year of life, although this may be an overestimation of these contents. Recent introduction of lower-protein and -energy formulas in full-term infants led us to systematically review the literature for its effects on growth. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, our inclusion criteria were studies that enrolled healthy full-term infants and evaluated lower-protein or lower-energy formula, reported anthropometr

SUBMITTER: Abrams SA 

PROVIDER: S-EPMC4352176 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature