GASS: genome structural annotation for Eukaryotes based on species similarity.

ABSTRACT:

Background

With the development of high-throughput sequencing techniques, more and more genomes were sequenced and assembled. However, annotating a genome's structure rapidly and expressly remains challenging. Current eukaryotic genome annotations require various, abundant supporting data, such as: species-specific and cross-species protein sequences, ESTs, cDNA and RNA-Seq data. Collecting those data and merging their analytical results to achieve a consistent complete annotation is a complex, time and cost consuming task.

Results

In our study, we proposed a fast and easy-to-use computational tool: GASS (Genome Annotation based on Species Similarity). It annotates a eukaryotic genome based on only the annotations from another similar species. With aligning the exons' sequen

SUBMITTER: Wang Y 

PROVIDER: S-EPMC4352269 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature