Regional myocardial three-dimensional principal strains during postinfarction remodeling.

ABSTRACT:

Background

The purpose of this study was to quantify myocardial three-dimensional (3D) principal strains as the left ventricle (LV) remodels after myocardial infarction (MI). Serial quantification of myocardial strains is important for understanding the mechanical response of the LV to MI. Principal strains convert the 3D LV wall-based strain matrix with three normal and three shear elements, to a matrix with three nonzero normal elements, thereby eliminating the shear elements, which are difficult to physically interpret.

Methods

The study was designed to measure principal strains of the remote, border zone, and infarct regions in a porcine model of post-MI LV remodeling. Magnetic resonance imaging was used to measure function and strain at baseline, 1 week, and 4 weeks aft

SUBMITTER: Pilla JJ 

PROVIDER: S-EPMC4352409 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature