Optimal systolic blood pressure target, time to intensification, and time to follow-up in treatment of hypertension: population based retrospective cohort study.

ABSTRACT:

Objectives

To investigate the optimal systolic blood pressure goal above which new antihypertensive medications should be added or doses of existing medications increased ("systolic intensification threshold") and to determine the relation between delays in medication intensification and follow-up and the risk of cardiovascular events or death.

Design

Retrospective cohort study.

Setting

Primary care practices in the United Kingdom, 1986-2010.

Participants

88 756 adults with hypertension from The Health Improvement Network nationwide primary care research database.

Main outcome measures

Rates of acute cardiovascular events or death from any cause for patients with different hypertension treatment strategies (defined by systolic intensification threshold,

SUBMITTER: Xu W 

PROVIDER: S-EPMC4353282 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature