Superficial layer pyramidal cells communicate heterogeneously between multiple functional domains of cat primary visual cortex.

ABSTRACT: The axons of pyramidal neurons in the superficial layers of the neocortex of higher mammals form lateral networks of discrete clusters of synaptic boutons. In primary visual cortex the clusters are reported to link domains that share the same orientation preferences, but how individual neurons contribute to this network is unknown. Here we performed optical imaging to record the intrinsic signal, which is an indirect measure of neuronal firing, and determined the global map of orientation preferences in the cat primary visual system. In the same experiment, single cells were recorded and labelled intracellularly. We found that individual axons arborise within the retinotopic representation of the classical receptive field, but their bouton clusters were not aligned along their preferred ax

SUBMITTER: Martin KA 

PROVIDER: S-EPMC4354012 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature