Atorvastatin and prevention of contrast induced nephropathy following coronary angiography.

ABSTRACT:

Background

Contrast induced nephropathy (CIN) is one of the most common complications after radiographic procedures using intravascular radiocontrast media. The aim of the current study was to assess the effect of atorvastatin on prevention of CIN in patients undergoing coronary angiography.

Materials and methods

In a clinical trial study, 200 patients referred for angiography were randomly divided into two groups of using 80 mg atorvastatin and placebo before the procedure. Furthermore, 100 patients who were under chronic treatment of statins were included as the third group. Serum creatinine (Scr) levels before and after the procedure were evaluated and incidence of CIN (post-procedural Scr of >0.5 mg/dl or >25% from baseline) was assessed.

Results

Mean age of the p

SUBMITTER: Bidram P 

PROVIDER: S-EPMC4354054 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature