Genetic diversity of Plasmodium vivax population before elimination of malaria in Hainan Province, China.

ABSTRACT:

Background

Hainan Province is one of the most severe endemic regions with high transmission of Plasmodium falciparum and Plasmodium vivax in China. However, the incidence of P. falciparum and P. vivax has dropped dramatically since 2007 and a national elimination malaria programme (NEMP) was launched after 2010. To better understand the genetic information on P. vivax population before elimination of malaria in Hainan Province, the extent of genetic diversity of P. vivax isolates in Hainan Province was investigated using four polymorphic genetic markers, including P. vivax merozoite surface proteins 1, 3α, and 3β (pvmsp-1, pvmsp-3α, and pvmsp-3β) and circumsporozoite protein (pvcsp).

Methods

Isolates of P. vivax (n = 27) from Hainan Province were collected from 2009 to 2010

SUBMITTER: Li YC 

PROVIDER: S-EPMC4354742 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature