High versus low-dose rate brachytherapy for cervical cancer.

ABSTRACT:

Objectives

Brachytherapy plays an important role in the treatment of cervical cancer. While small trials have shown comparable survival outcomes between high (HDR) and low-dose rate (LDR) brachytherapy, little data is available in the US. We examined the utilization of HDR brachytherapy and analyzed the impact of type of brachytherapy on survival for cervical cancer.

Methods

Women with stages IB2-IVA cervical cancer treated with primary (external beam and brachytherapy) radiotherapy between 2003-2011 and recorded in the National Cancer Database (NCDB) were analyzed. Generalized linear mixed models and Cox proportional hazards regression were used to examine predictors of HDR brachytherapy use and the association between HDR use and survival.

Results

A total of 10,564

SUBMITTER: Patankar SS 

PROVIDER: S-EPMC4355179 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature